Preferred Label : amino acid motifs;
MeSH definition : Commonly observed structural components of proteins formed by simple combinations
of adjacent secondary structures. A commonly observed structure may be composed of
a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.; Three-dimensional protein structural elements that are composed of a combination of
secondary structures. They include HELIX-LOOP-HELIX MOTIFS and ZINC FINGERS. Motifs
are typically the most conserved regions of PROTEIN DOMAINS and are critical for domain
function. However, the same motif may occur in proteins or enzymes with different
functions.;
MeSH synonym : amino acid motif; protein motif; motif, amino acid; motif, protein; motifs, amino acid; protein motifs; motifs, protein; AA Motifs; AA Motif; Motif, AA; Motifs, AA;
MeSH Hyperonym : protein structure, supersecondary; Protein Structures, Supersecondary; Supersecondary Protein Structures; Supersecondary Protein Structure;
MeSH annotation : IM general; coord NIM with specific protein (IM); PROTEIN DOMAINS see PROTEIN STRUCTURE,
TERTIARY is available; if the amino acid motif is a representative of conserved sequence
then also index CONSENSUS SEQUENCE; DF: AA MOTIFS; IM general only; coordinate NIM with specific protein;
Origin ID : D020816;
UMLS CUI : C0752190;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- See also
- Semantic type(s)
Commonly observed structural components of proteins formed by simple combinations
of adjacent secondary structures. A commonly observed structure may be composed of
a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.
Three-dimensional protein structural elements that are composed of a combination of
secondary structures. They include HELIX-LOOP-HELIX MOTIFS and ZINC FINGERS. Motifs
are typically the most conserved regions of PROTEIN DOMAINS and are critical for domain
function. However, the same motif may occur in proteins or enzymes with different
functions.
