mibefradil - CISMeF

Preferred Label : mibefradil;

MeSH definition : A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE.;

CISMeF synonym : 116666-63-8 (Mibefradil dihydrochloride); roche brand of mibefradil dihydrochloride;

MeSH hyponym : posicor; mibefradil dihydrochloride; ro 40-5967; Ro 40 5967; Ro 405967;

MeSH CAS label : (1S,2S)-(2-((3-(2-benzimidazolyl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate;

MeSH Related Number : mibefradil dihydrochloride; 116644-53-2 (Mibefradil); 116666-63-8 (dihydrochloride); 842TUP3PQ8;

Registry Number MeSH : 116644-53-2;

Related CAS MeSH : 842TUP3PQ8 (Mibefradil dihydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Mibefradil;

Is substance : O;

UNII : 27B90X776A;

InChIKey : HBNPJJILLOYFJU-VMPREFPWSA-N;

Details

Origin ID

D020748;

UMLS CUI

C0286185;

ATC code(s)
- mibefradil [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Mibefradil [ICD-11 Extension code]
Pharmacological action(s)
- Cytochrome P-450 CYP1A2 Inhibitors [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
- calcium channel blockers [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- mibefradil [MeSH concept]
- mibefradil dihydrochloride [MeSH concept]
- posicor [MeSH concept]
- ro 40-5967 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mibefradil [NCIt concept]
- Mibefradil (substance) [SNOMED CT concept]
- Product containing mibefradil (medicinal product) [SNOMED CT concept]
- mibefradil [ATC Code]

Keyword's position in hierarchy(ies) :

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