peptide elongation factor 1

Preferred Label : peptide elongation factor 1;

MeSH definition : Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.;

MeSH synonym : ef-1h; elongation factor 1; ef 1h; ef 1; ef-1;

CISMeF synonym : 1, ef;

MeSH hyponym : elongation factor 1gamma; elongation factor 1delta; elongation factor 1alpha; elongation factor 1beta; EF-1gamma; EF 1gamma; EF-1delta; EF 1delta; EF-1alpha; EF 1alpha; EF-1beta; EF 1beta;

Is substance : O;

Details

Origin ID

D020648;

UMLS CUI

C0059036;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Elongation Factor 1 [NCIt concept]
- Elongation Factor 1-Alpha 1 [NCIt concept]
- Elongation Factor 1-Beta [NCIt concept]
- Elongation Factor 1-Delta [NCIt concept]
- Elongation Factor 1-Gamma [NCIt concept]
Indexing information
- NSC 122281 [MeSH Supplementary Concept]
- NSC 36398 [MeSH Supplementary Concept]
- NSC 4347 [MeSH Supplementary Concept]
Record concept(s)
- elongation factor 1alpha [MeSH concept]
- elongation factor 1beta [MeSH concept]
- elongation factor 1delta [MeSH concept]
- elongation factor 1gamma [MeSH concept]
- peptide elongation factor 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CAM1 protein, S cerevisiae [MeSH Supplementary Concept]
- EEF1A1 protein, human [MeSH Supplementary Concept]
- EEF1A1 protein, rat [MeSH Supplementary Concept]
- EEF1A2 protein, human [MeSH Supplementary Concept]
- EEF1D protein, human [MeSH Supplementary Concept]
- Eef1a1 protein, mouse [MeSH Supplementary Concept]
- Eef1a2 protein, mouse [MeSH Supplementary Concept]
- Eef1a2 protein, rat [MeSH Supplementary Concept]
- GUF1 protein, human [MeSH Supplementary Concept]
- TEF1 protein, S cerevisiae [MeSH Supplementary Concept]
- TEF2 protein, S cerevisiae [MeSH Supplementary Concept]
- eEF1A-1 protein, mouse [MeSH Supplementary Concept]
- eEF1B-alpha protein, human [MeSH Supplementary Concept]
- eEF1B-beta protein, human [MeSH Supplementary Concept]
- eEF1B-delta protein, human [MeSH Supplementary Concept]
- eEF1B-gamma protein, human [MeSH Supplementary Concept]
- eef1a1o protein, Xenopus [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Elongation Factor 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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