heteroduplex analysis

Preferred Label : heteroduplex analysis;

MeSH definition : A method of detecting gene mutation by mixing PCR-amplified mutant and wild-type DNA followed by denaturation and reannealing. The resultant products are resolved by gel electrophoresis, with single base substitutions detectable under optimal electrophoretic conditions and gel formulations. Large base pair mismatches may also be analyzed by using electron microscopy to visualize heteroduplex regions.;

MeSH synonym : analyses, heteroduplex; analysis, heteroduplex; heteroduplex analyses;

Details

Origin ID

D020180;

UMLS CUI

C0600507;

Allowable qualifiers
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- ethics [MeSH Qualifier]
- history [MeSH Qualifier]
- instrumentation [MeSH Qualifier]
- methods [MeSH Qualifier]
- standards [MeSH Qualifier]
- statistics and numerical data [MeSH Qualifier]
- trends [MeSH Qualifier]
- veterinary [MeSH Qualifier]
Currated CISMeF NLP mapping
- Heteroduplex Analysis [NCIt concept]
Record concept(s)
- heteroduplex analysis [MeSH concept]
See also
- base pair mismatch [MeSH Descriptor]
- nucleic acid heteroduplexes [MeSH Descriptor]
Semantic type(s)
- Molecular Biology Research Technique [UMLS semantic type]
UMLS correspondences (same concept)
- Heteroduplex Analysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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