pinacidil - CISMeF

Preferred Label : pinacidil;

MeSH definition : A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed);

MeSH hyponym : pindac; pinacidil anhydrous; Anhydrous, Pinacidil;

MeSH CAS label : guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropylmonohydrate), ( -)-;

MeSH Related Number : pinacidil anhydrous; 60560-33-0 (anhydrous); 85371-64-8 (Pinacidil);

Registry Number MeSH : 85371-64-8;

Related CAS MeSH : 60560-33-0 (Pinacidil anhydrous);

Wikipedia link : https://en.wikipedia.org/wiki/Pinacidil;

Is substance : O;

UNII : 7B0ZZH8P2W;

InChIKey : AFJCNBBHEVLGCZ-UHFFFAOYSA-N;

Details

Origin ID

D020110;

UMLS CUI

C0071074;

ATC code(s)
- guanidine derivatives [ATC Code]
- other antihypertensives and diuretics [ATC Code]
- pinacidil [ATC Code]
- pinacidil and diuretics [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Pinacidil [ICHI extension code]
Currated CISMeF NLP mapping
- Pinacidil [Substance BNPC]
- Pinacidil [ICD-11 Extension code]
- Pinacidil [NCIt concept]
Pharmacological action(s)
- antihypertensive agents [MeSH Descriptor]
- membrane transport modulators [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- pinacidil [MeSH concept]
- pinacidil anhydrous [MeSH concept]
- pindac [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-pyridyl pinacidil [MeSH Supplementary Concept]
- N-(4-difluoromethoxyphenyl)-N'-pinacolyl-N''-cyanoguanidine [MeSH Supplementary Concept]
- pinacidil pyridine N-oxide [MeSH Supplementary Concept]
- washington university solution [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pinacidil [ICD-11 Extension code]
- Pinacidil [NCIt concept]
- pinacidil [ATC Code]
Validated automatic mappings to BTNT
- Pinacidil Anhydrous [NCIt concept]
- pinacidil [ATC Code]

Keyword's position in hierarchy(ies) :

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