MeSH definition : The joining of RNA from two different genes. One type of trans-splicing is the spliced
leader type (primarily found in protozoans such as trypanosomes and in lower invertebrates
such as nematodes) which results in the addition of a capped, noncoding, spliced leader
sequence to the 5' end of mRNAs. Another type of trans-splicing is the discontinuous
group II introns type (found in plant/algal chloroplasts and plant mitochondria) which
results in the joining of two independently transcribed coding sequences. Both are
mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells
are also capable of trans-splicing.;
MeSH synonym : rna trans-splicing; trans rna splicing; splicing, trans; rna trans splicing; trans-splicings, rna; rna splicing, trans; trans splicing;
MeSH annotation : note category: a physiol process taking place within the cell nucleus; do not confuse
with DNA, RECOMBINANT; CLONING, MOLECULAR; or GENETIC ENGINEERING;
Wikipedia link : https://en.wikipedia.org/wiki/Trans-splicing;
The joining of RNA from two different genes. One type of trans-splicing is the spliced
leader type (primarily found in protozoans such as trypanosomes and in lower invertebrates
such as nematodes) which results in the addition of a capped, noncoding, spliced leader
sequence to the 5' end of mRNAs. Another type of trans-splicing is the discontinuous
group II introns type (found in plant/algal chloroplasts and plant mitochondria) which
results in the joining of two independently transcribed coding sequences. Both are
mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells
are also capable of trans-splicing.
Allowable qualifiers