MeSH definition : A hemostatic disorder characterized by a poor anticoagulant response to activated
protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded
by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause
of APC resistance.;
A hemostatic disorder characterized by a poor anticoagulant response to activated
protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded
by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause
of APC resistance.