MeSH definition : Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They
consist of an extracellular alpha chain which is disulfide-linked to the transmembrane
beta chain. The cytoplasmic portion contains the catalytic domain and sites critical
for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEINS
C-MET are associated with papillary renal carcinoma and other neoplasia.; Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They
consist of an extracellular alpha chain which is disulfide-linked to the transmembrane
beta chain. The cytoplasmic portion contains the catalytic domain and sites critical
for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated
with papillary renal carcinoma and other neoplasia.;
MeSH synonym : met proto oncogene proteins; receptor, scatter factor; receptor, hgf; receptor, hepatocyte growth factor; hepatocyte growth factor receptor; hgf receptor; scatter factor receptor; c-met proteins; c met proteins; met proto-oncogene proteins; proto-oncogene proteins, met; proto oncogene proteins c met; MET Receptor Tyrosine Kinase; c-Met Receptor Tyrosine Kinase; c Met Receptor Tyrosine Kinase; MET Proto-Oncogene, Receptor Tyrosine Kinase; MET Proto Oncogene, Receptor Tyrosine Kinase;
Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They
consist of an extracellular alpha chain which is disulfide-linked to the transmembrane
beta chain. The cytoplasmic portion contains the catalytic domain and sites critical
for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEINS
C-MET are associated with papillary renal carcinoma and other neoplasia. Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They
consist of an extracellular alpha chain which is disulfide-linked to the transmembrane
beta chain. The cytoplasmic portion contains the catalytic domain and sites critical
for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated
with papillary renal carcinoma and other neoplasia.