trinucleotide repeat expansion

Preferred Label : trinucleotide repeat expansion;

MeSH definition : An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.;

MeSH synonym : trinucleotide repeats, expanded; expansions, trinucleotide repeat; repeat, expanded trinucleotide; expanded trinucleotide repeats; expansion, trinucleotide repeat; repeat expansion, trinucleotide; repeat expansions, trinucleotide; trinucleotide repeat expansions; expanded trinucleotide repeat; repeats, expanded trinucleotide; trinucleotide repeat, expanded;

Details

Origin ID

D019680;

UMLS CUI

C0524894;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Indexing information
- MYL4 protein, human [MeSH Supplementary Concept]
Record concept(s)
- trinucleotide repeat expansion [MeSH concept]
See also
- anticipation, genetic [MeSH Descriptor]
- chromosome fragile sites [MeSH Descriptor]
- chromosome fragility [MeSH Descriptor]
- fragile x syndrome [MeSH Descriptor]
- myotonic dystrophy [MeSH Descriptor]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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