okadaic acid - CISMeF

Preferred Label : okadaic acid;

MeSH definition : A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41); A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. It is produced by DINOFLAGELLATES and causes diarrhetic SHELLFISH POISONING.;

MeSH synonym : ocadaic acid;

CISMeF synonym : acid, ocadaic; acid, okadaic;

MeSH Related Number : 78111-17-8 (Okadaic acid);

Registry Number MeSH : 78111-17-8;

Wikipedia link : https://en.wikipedia.org/wiki/Okadaic acid;

Is substance : O;

UNII : 1W21G5Q4N2;

InChIKey : QNDVLZJODHBUFM-WFXQOWMNSA-N;

Details

Origin ID

D019319;

UMLS CUI

C0069389;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- okadaic acid [Substance BNPC]
Currated CISMeF NLP mapping
- Okadaic acid (substance) [SNOMED CT concept]
Indexing information
- EIF1 protein, human [MeSH Supplementary Concept]
- LUC7L3 protein, human [MeSH Supplementary Concept]
- dinophysistoxin 1 [MeSH Supplementary Concept]
- okadaic acid receptor [MeSH Supplementary Concept]
- okadaic acid-sensitive phosphatase [MeSH Supplementary Concept]
Pharmacological action(s)
- carcinogens [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- ionophores [MeSH Descriptor]
Record concept(s)
- okadaic acid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 19-epi-okadaic acid [MeSH Supplementary Concept]
- 2-epi-dinophysistoxin-2 [MeSH Supplementary Concept]
- 27-O-acetyldinophysistoxin 1 [MeSH Supplementary Concept]
- 27-O-acetylokadaic acid [MeSH Supplementary Concept]
- 7-deoxyokadaic acid [MeSH Supplementary Concept]
- 7-hydroxymethyl-2-methylene-octa-4,7-dienyl okadaate [MeSH Supplementary Concept]
- DTX-6 compound [MeSH Supplementary Concept]
- DTX5c compound [MeSH Supplementary Concept]
- belizeanic acid [MeSH Supplementary Concept]
- corozalic acid [MeSH Supplementary Concept]
- dinophysistoxin 1 [MeSH Supplementary Concept]
- dinophysistoxin 2 [MeSH Supplementary Concept]
- dinophysistoxin 3 [MeSH Supplementary Concept]
- dinophysistoxin 4 [MeSH Supplementary Concept]
- dinophysistoxin 5 [MeSH Supplementary Concept]
- okadaic acid diol ester [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Okadaic acid (substance) [SNOMED CT concept]
- okadaic acid [Substance BNPC]

Keyword's position in hierarchy(ies) :

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