Preferred Label : spectrometry, mass, matrix-assisted laser desorption-ionization;
MeSH definition : A mass spectrometric technique that is used for the analysis of large biomolecules.
Analyte molecules are embedded in an excess matrix of small organic molecules that
show a high resonant absorption at the laser wavelength used. The matrix absorbs the
laser energy, thus inducing a soft disintegration of the sample-matrix mixture into
free (gas phase) matrix and analyte molecules and molecular ions. In general, only
molecular ions of the analyte molecules are produced, and almost no fragmentation
occurs. This makes the method well suited for molecular weight determinations and
mixture analysis.;
MeSH synonym : laser desorption ionization mass spectrometry, matrix assisted; maldi; maldi ms; maldi-ms; mald-ms; mass spectrometry, matrix assisted laser desorption ionization; mass spectrometry, matrix-assisted laser desorption-ionization; mass spectroscopy, matrix-assisted laser desorption-ionization; matrix assisted laser desorption ionization mass spectrometry; matrix-assisted laser desorption-ionization mass spectrometry; ms-mald; spectroscopy, mass, matrix-assisted laser desorption-ionization; laser desorption-ionization mass spectrometry, matrix-assisted; mass spectroscopy, matrix assisted laser desorption ionization;
MeSH hyponym : surface enhanced laser desorption ionization mass spectrometry; SELDI-TOF-MS;
Origin ID : D019032;
UMLS CUI : C0282597;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A mass spectrometric technique that is used for the analysis of large biomolecules.
Analyte molecules are embedded in an excess matrix of small organic molecules that
show a high resonant absorption at the laser wavelength used. The matrix absorbs the
laser energy, thus inducing a soft disintegration of the sample-matrix mixture into
free (gas phase) matrix and analyte molecules and molecular ions. In general, only
molecular ions of the analyte molecules are produced, and almost no fragmentation
occurs. This makes the method well suited for molecular weight determinations and
mixture analysis.
