MeSH definition : A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting
utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves
DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from
Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed);
MeSH synonym : footprinting, dna; dna footprintings; footprintings, dna;
Related MeSH term : footprints, DNA; DNA Footprint; DNA Footprints; Footprint, DNA;
MeSH annotation : DNA FINGERPRINTING is available;
A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting
utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves
DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from
Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)