Preferred Label : Hyaluronan Receptors;
MeSH definition : Acidic sulfated integral membrane glycoproteins expressed in several alternatively
spliced and variable glycosylated forms on a wide variety of cell types including
mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes,
and fibroblasts. CD44 antigens are the principle cell surface receptors for hyaluronate
and this interaction mediates binding of lymphocytes to high endothelial venules.
(From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156); Acidic sulfated integral membrane glycoproteins expressed in several alternatively
spliced and variable glycosylated forms on a wide variety of cell types including
mature T-cells, B-cells, medullary THYMOCYTES; GRANULOCYTES; MACROPHAGES; erythrocytes,
and fibroblasts. Their interaction with HYALURONIC ACID mediates binding of lymphocytes
to high endothelial VENULES.;
MeSH synonym : receptors, hyaluronan; cd44 antigen; hyaluronan-binding protein; hyaluronan binding protein; antigen, cd44; hyaluronan receptor; receptor, hyaluronan; hyaluronic acid binding protein; cd44 antigens; Antigens, CD44; Chondroitin Sulfate Proteoglycan 8;
MeSH annotation : lymphocyte homing receptors;
Wikipedia link : https://en.wikipedia.org/wiki/Antigens, cd44;
Is substance : O;
Origin ID : D018960;
UMLS CUI : C0243982;
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Acidic sulfated integral membrane glycoproteins expressed in several alternatively
spliced and variable glycosylated forms on a wide variety of cell types including
mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes,
and fibroblasts. CD44 antigens are the principle cell surface receptors for hyaluronate
and this interaction mediates binding of lymphocytes to high endothelial venules.
(From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156)
Acidic sulfated integral membrane glycoproteins expressed in several alternatively
spliced and variable glycosylated forms on a wide variety of cell types including
mature T-cells, B-cells, medullary THYMOCYTES; GRANULOCYTES; MACROPHAGES; erythrocytes,
and fibroblasts. Their interaction with HYALURONIC ACID mediates binding of lymphocytes
to high endothelial VENULES.
