Preferred Label : replication origin;
MeSH definition : A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds
bidirectionally or unidirectionally. It contains the sites where the first separation
of the complementary strands occurs, a primer RNA is synthesized, and the switch from
primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical
and Molecular, 5th ed);
MeSH synonym : ori region; ori regions; origin of replication; origin, replication; origins, replication; region, ori; regions, ori; replication origins;
Wikipedia link : https://en.wikipedia.org/wiki/Origin of replication;
Is substance : O;
Origin ID : D018741;
UMLS CUI : C0242961;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds
bidirectionally or unidirectionally. It contains the sites where the first separation
of the complementary strands occurs, a primer RNA is synthesized, and the switch from
primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical
and Molecular, 5th ed)
