Preferred Label : cross-over studies;
MeSH definition : Studies comparing two or more treatments or interventions in which the subjects or
patients, upon completion of the course of one treatment, are switched to another.
In the case of two treatments, A and B, half the subjects are randomly allocated to
receive these in the order A, B and half to receive them in the order B, A. A criticism
of this design is that effects of the first treatment may carry over into the period
when the second is given. (Last, A Dictionary of Epidemiology, 2d ed);
MeSH synonym : crossover trials; studies, crossover; study, crossover; cross-over trials; cross over trials; trial, cross-over; trials, cross-over; trial, crossover; trials, crossover; cross-over study; studies, cross-over; study, cross-over; crossover studies; crossover study; cross over studies;
Related MeSH term : Cross-Over design; Cross Over Design; Cross-Over Designs; Design, Cross-Over; Designs, Cross-Over; Crossover Design; Crossover Designs; Design, Crossover; Designs, Crossover;
MeSH annotation : usually drug or other ther study; IM GEN only; coord NIM with specific ther (IM);
coord NIM also with any other study design such as RANDOM ALLOCATION; DOUBLE-BLIND
METHOD; etc. (NIM); when pertinent add CLINICAL TRIAL (PT) or RANDOMIZED CONTROLLED
TRIAL (PT); no qualif; IM general only; when pertinent add CLINICAL TRIAL (PT) or RANDOMIZED CONTROLLED TRIAL
(PT);
Wikipedia link : https://en.wikipedia.org/wiki/Cross-over design;
Origin ID : D018592;
UMLS CUI : C0150097;
Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
Studies comparing two or more treatments or interventions in which the subjects or
patients, upon completion of the course of one treatment, are switched to another.
In the case of two treatments, A and B, half the subjects are randomly allocated to
receive these in the order A, B and half to receive them in the order B, A. A criticism
of this design is that effects of the first treatment may carry over into the period
when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
