Preferred Label : centrosome;
MeSH definition : The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous
material called the pericentriolar region. During interphase, the centrosome nucleates
microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to
form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).; An organelle near the nucleus of the cell consisting (in animals and organisms that
have CILIA) of two CENTRIOLES, and the surrounding pericentriolar material. It functions
as the primary MICROTUBULE-ORGANIZING CENTER during the eukaryotic CELL CYCLE (https://doi.org/10.1038/nrm2180).;
MeSH synonym : centrosomes;
MeSH hyponym : pericentriolar region; Pericentriolar Regions; Region, Pericentriolar; Regions, Pericentriolar; Matrix, Pericentriolar; Pericentriolar Matrices; Pericentriolar Material; Material, Pericentriolar; Pericentriolar Materials;
Wikipedia link : https://en.wikipedia.org/wiki/Centrosome;
Origin ID : D018385;
UMLS CUI : C0242608;
Allowable qualifiers
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous
material called the pericentriolar region. During interphase, the centrosome nucleates
microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to
form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).
An organelle near the nucleus of the cell consisting (in animals and organisms that
have CILIA) of two CENTRIOLES, and the surrounding pericentriolar material. It functions
as the primary MICROTUBULE-ORGANIZING CENTER during the eukaryotic CELL CYCLE (https://doi.org/10.1038/nrm2180).
