receptors, GABA

Preferred Label : receptors, GABA;

MeSH definition : Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.;

MeSH synonym : receptor, gamma-aminobutyric acid; receptors, gamma aminobutyric acid; gaba receptor; gaba receptors; receptors, gamma-aminobutyric acid; gamma-aminobutyric acid receptor; gamma aminobutyric acid receptor; gamma-aminobutyric acid receptors; gamma aminobutyric acid receptors; receptor, gaba;

MeSH annotation : GEN; prefer specifics; DF: RECEPT GABA;

Wikipedia link : https://en.wikipedia.org/wiki/Gaba receptors;

Is substance : O;

Details

Origin ID

D018079;

UMLS CUI

C0206518;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- gamma-aminobutyric acid type A receptor subunit alpha1 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit alpha2 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit alpha3 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit alpha4 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit alpha5 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit alpha6 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit beta1 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit beta2 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit beta3 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit delta [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit epsilon [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit gamma1 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit gamma2 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit pi [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit rho1 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit rho2 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit rho3 [HGNC gene]
- gamma-aminobutyric acid type A receptor subunit theta [HGNC gene]
Indexing information
- 6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzothiophen-4(5H)-one [MeSH Supplementary Concept]
- KN 244 [MeSH Supplementary Concept]
- ethyl 6-benzyloxy-beta-carboline-3-carboyxlate [MeSH Supplementary Concept]
Record concept(s)
- receptors, GABA [MeSH concept]
Related MeSH Supplementary Concept(s)
- EXP-1 protein, C elegans [MeSH Supplementary Concept]
- GABA-C receptor [MeSH Supplementary Concept]
- GABA-C rho3 receptor, mouse [MeSH Supplementary Concept]
- Gabrb2 protein, mouse [MeSH Supplementary Concept]
- LGC-35 protein, C elegans [MeSH Supplementary Concept]
- TSPO protein, human [MeSH Supplementary Concept]
- TSPO protein, zebrafish [MeSH Supplementary Concept]
- bzrp protein, mouse [MeSH Supplementary Concept]
- pfetin protein, mouse [MeSH Supplementary Concept]
- rho1 GABA(C) receptor, human [MeSH Supplementary Concept]
Related MeSH term(s)
- GABA agonists [MeSH Descriptor]
- GABA antagonists [MeSH Descriptor]
See also
- gaba plasma membrane transport proteins [MeSH Descriptor]
- gamma-aminobutyric acid [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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