receptors, calcitonin gene-related peptide

Preferred Label : receptors, calcitonin gene-related peptide;

MeSH definition : Cell surface proteins that bind CALCITONIN GENE-RELATED PEPTIDE with high affinity and trigger intracellular changes which influence the behavior of cells. CGRP receptors are present in both the CENTRAL NERVOUS SYSTEM and the periphery. They are formed via the heterodimerization of the CALCITONIN RECEPTOR-LIKE PROTEIN and RECEPTOR ACTIVITY-MODIFYING PROTEIN 1.;

MeSH synonym : calcitonin gene-related peptide receptors; cgrp receptor; cgrp receptors; receptors, cgrp; calcitonin gene related peptide receptor; calcitonin-gene related peptide receptor; calcitonin gene related peptide receptors; receptors, calcitonin gene related peptide;

CISMeF synonym : receptor, cgrp;

Is substance : O;

Details

Origin ID

D018015;

UMLS CUI

C0108066;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Calcitonin receptor-like receptor [OMIM gene]
- calcitonin gene-related peptide receptor activity [GO term]
Indexing information
- 1-(N(2)-(3,4-dibromo-N-((4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl)carbonyl)tyrosyl)lysyl)-4-(4-pyridinyl)piperazine [MeSH Supplementary Concept]
- 2-(8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro(4.5)dec-9-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro(indene-2,3'-pyrrolo(2,3-b)pyridin)-5-yl)acetamide [MeSH Supplementary Concept]
- 4-(2-oxo-2,3-dihydrobenzimidazol-1-yl)piperidine-1-carboxylic acid (1-(3,5-dibromo-4-hydroxybenzyl)-2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)amide [MeSH Supplementary Concept]
- 4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide [MeSH Supplementary Concept]
- MK 2918 [MeSH Supplementary Concept]
- MK-8825 [MeSH Supplementary Concept]
- N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl))-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide [MeSH Supplementary Concept]
- alpha-calcitonin gene-related peptide, ethylamide-Cys(2,7)- [MeSH Supplementary Concept]
- calcitonin gene-related peptide (8-37) [MeSH Supplementary Concept]
- calcitonin gene-related peptide, (acetylmethoxy)cysteinyl(2,7)- [MeSH Supplementary Concept]
- olcegepant [MeSH Supplementary Concept]
Record concept(s)
- receptors, calcitonin Gene-Related peptide [MeSH concept]
Related MeSH Supplementary Concept(s)
- CRCP protein, human [MeSH Supplementary Concept]
- crcp protein, mouse [MeSH Supplementary Concept]
- crcp protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- Calcitonin Gene-Related Peptide Receptor Antagonists [MeSH Descriptor]
See also
- Calcitonin Gene-Related Peptide Receptor Antagonists [MeSH Descriptor]
- calcitonin gene-related peptide [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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