receptors, sigma

Preferred Label : receptors, sigma;

MeSH definition : A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.;

MeSH synonym : opioid receptors, sigma; receptors, opioid, sigma; receptors, sigma opioid; sigma opioid receptors; sigma receptor; sigma receptors; receptor, sigma;

MeSH annotation : opioid receptors; DF: RECEPT SIGMA;

Is substance : O;

Details

Origin ID

D017480;

UMLS CUI

C0074504;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Indexing information
- 1-(2-phenethyl)-4-(2-pyridyl)piperazine [MeSH Supplementary Concept]
- 1-(3-biphenyl-4-ylbutyl)piperidine [MeSH Supplementary Concept]
- 1-(3-phenylpropyl)piperidine [MeSH Supplementary Concept]
- 2-((1-adamantyl(methyl)amino)methyl)-1-phenylcyclopropanecarboxylic acid [MeSH Supplementary Concept]
- 2-(3,4-dichlorophenyl)-N-ethyl-N-(2-piperidin-1-ylethyl)ethanamine [MeSH Supplementary Concept]
- 2-(methyl(3-phenylpropyl)amino)cyclohexanol [MeSH Supplementary Concept]
- 2-(methyl(phenethyl)amino)cyclohexanol [MeSH Supplementary Concept]
- 3-(hexahydroazepin-1-yl)-1-(3-chloro-4-cyclohexylphenyl)-1-propene hydrochloride [MeSH Supplementary Concept]
- 4-(2-((5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine [MeSH Supplementary Concept]
- 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butyl 4-phenylbutyrate [MeSH Supplementary Concept]
- 4-(4-ethyl-piperazin-1-yl)-1-(2,3,4-trihydroxyphenyl)butan-1-one [MeSH Supplementary Concept]
- 6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo(d)thiazol-2(3H)-one [MeSH Supplementary Concept]
- 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone hydrochloride [MeSH Supplementary Concept]
- 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo(d)oxazol-2(3H)-one [MeSH Supplementary Concept]
- BD 1008 [MeSH Supplementary Concept]
- F281 compound [MeSH Supplementary Concept]
- L 687384 [MeSH Supplementary Concept]
- N,N-dibutyl-3-(4-nitrophenyl)propylamine [MeSH Supplementary Concept]
- N-((benzofuran-2-yl)methyl)-N'-(4'-methoxybenzyl)piperazine [MeSH Supplementary Concept]
- N-(1-phenylpropionyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- N-(1-phenylpropionyl)-4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin [MeSH Supplementary Concept]
- N-(N-benzylpiperidin-4-yl)-2-fluorobenzamide [MeSH Supplementary Concept]
- N-(N-benzylpiperidin-4-yl)-2-iodobenzamide [MeSH Supplementary Concept]
- N-(N-benzylpiperidin-4-yl)-4-iodobenzamide [MeSH Supplementary Concept]
- PB28 compound [MeSH Supplementary Concept]
- PB28 compound [MeSH Supplementary Concept]
- SA 4503 [MeSH Supplementary Concept]
- SR 31747 [MeSH Supplementary Concept]
- SR 31747 [MeSH Supplementary Concept]
- dimethyl-carbamic acid 2,3-bis-dimethylcarbamoyloxy-6-(4-ethylpiperazine-1-carbonyl)phenyl ester [MeSH Supplementary Concept]
- m-(p-chlorobenzyloxy)-N-cyclopropylmethyl-N-methylbenzylamine [MeSH Supplementary Concept]
- methyl 2-((4-hydroxy-4-phenylpiperidin-1-yl)methyl)-1-(4-methylphenyl)cyclopropanecarboxylate [MeSH Supplementary Concept]
Record concept(s)
- receptors, sigma [MeSH concept]
Related MeSH Supplementary Concept(s)
- sigma-1 receptor [MeSH Supplementary Concept]
- sigma-2 receptor [MeSH Supplementary Concept]
- sigma1-binding protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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