MeSH definition : A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells
stop dividing and undergo terminal differentiation when treated with NERVE GROWTH
FACTOR, making the line a useful model system for NERVE CELL differentiation.;
MeSH annotation : PC stands for PheochromoCytoma; almost always NIM with no subheadings; check ANIMAL;
& RATS; do not routinely add PHEOCHROMOCYTOMA or ADRENAL GLAND NEOPLASMS;
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells
stop dividing and undergo terminal differentiation when treated with NERVE GROWTH
FACTOR, making the line a useful model system for NERVE CELL differentiation.