monocrotaline - CISMeF

Preferred Label : monocrotaline;

MeSH definition : A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.;

MeSH hyponym : monocrotaline, (all-xi)-Isomer; monocrotaline hydrochloride (13alpha,14alpha)-Isomer;

MeSH CAS label : 20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, (13alpha,14alpha)-;

MeSH Related Number : monocrotaline hydrochloride (13alpha,14alpha)-Isomer; monocrotaline, (all-xi)-Isomer; 315-22-0 (Monocrotaline); 83114-75-4 ((all-xi)-isomer); 901-82-6 (HCl(13alpha,14alpha)-isomer);

Registry Number MeSH : 315-22-0;

Related CAS MeSH : 901-82-6 (Monocrotaline hydrochloride (13alpha,14alpha)-Isomer); 83114-75-4 (Monocrotaline, (all-xi)-Isomer);

Is substance : O;

UNII : 73077K8HYV;

InChIKey : QVCMHGGNRFRMAD-XFGHUUIASA-N;

Details

Origin ID

D016686;

UMLS CUI

C0085241;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- monocrotaline [MeSH concept]
- monocrotaline hydrochloride (13alpha,14alpha)-Isomer [MeSH concept]
- monocrotaline, (all-xi)-Isomer [MeSH concept]
Related MeSH Supplementary Concept(s)
- 7-cysteinyldehydroretronecine [MeSH Supplementary Concept]
- dehydroretronecine [MeSH Supplementary Concept]
- monocrotaline pyrrole [MeSH Supplementary Concept]
- trichodesmine [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Monocrotaline (substance) [SNOMED CT concept]
- monocrotaline [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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