Preferred Label : lewy bodies;
MeSH definition : Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of
injured or fragmented neurons. The presence of Lewy bodies is the histological marker
of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may
be seen in other neurological conditions. They are typically found in the substantia
nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic
nuclei, and neocortex.;
MeSH synonym : lewy body;
CISMeF synonym : Lewy; bodies, lewy; body, lewy;
DeCS synonym : Eosinophilic Neuronal Cytoplasmic Inclusions;
Related MeSH term : Lewy Neurite; Neurite, Lewy;
MeSH annotation : LEWY BODY DISEASE is also available;
Wikipedia link : https://en.wikipedia.org/wiki/Lewy bodies;
Origin ID : D016631;
UMLS CUI : C0085200;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- HPO term
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of
injured or fragmented neurons. The presence of Lewy bodies is the histological marker
of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may
be seen in other neurological conditions. They are typically found in the substantia
nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic
nuclei, and neocortex.
