Preferred Label : frameshift mutation;
MeSH definition : A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into
a protein coding sequence is not divisible by three, thereby causing an alteration
in the READING FRAMES of the entire coding sequence downstream of the mutation. These
mutations may be induced by certain types of MUTAGENS or may occur spontaneously.;
MeSH synonym : out-of-frame mutation; mutations, frameshift; frameshift mutations; mutations, out-of-frame; mutation, out-of-frame; mutation, frame shift; mutations, frame shift; mutation, frameshift; out of frame mutation; out-of-frame mutations; frame shift mutation; frame shift mutations;
MeSH hyponym : Out-of-Frame insertion; Out-of-Frame deletion; Insertion, Out-of-Frame; Insertions, Out-of-Frame; Out of Frame Insertion; Out-of-Frame Insertions; Deletion, Out-of-Frame; Deletions, Out-of-Frame; Out of Frame Deletion; Out-of-Frame Deletions;
MeSH annotation : do not confuse with FRAMESHIFTING, RIBOSOMAL, physiology process & form of genetic
translation; do not confuse effects of drug & radiation on frameshift mutation with
drug- & radiation-induced frameshift mutation;
Wikipedia link : https://en.wikipedia.org/wiki/Frameshift mutation;
Origin ID : D016368;
UMLS CUI : C0079380;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Ne pas confondre avec
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into
a protein coding sequence is not divisible by three, thereby causing an alteration
in the READING FRAMES of the entire coding sequence downstream of the mutation. These
mutations may be induced by certain types of MUTAGENS or may occur spontaneously.
