macrophage-activating factors

Preferred Label : macrophage-activating factors;

MeSH definition : Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxic to tumors. They also modulate the expression of macrophage cell surface Ia antigens. One MAF is INTERFERON-GAMMA. Other factors antigenically distinct from IFN-gamma have also been identified.;

MeSH synonym : factors, macrophage-activating; macrophage activating factors;

MeSH annotation : a lymphokine; /biosyn /drug eff /physiol /ultrastruct permitted; DF: MAF;

Is substance : O;

Details

Origin ID

D016215;

UMLS CUI

C0079786;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- MAF bZIP transcription factor [ORDO Gene]
- Maf bzip transcription factor [OMIM gene]
Currated CISMeF NLP mapping
- Macrophage activating factor (substance) [SNOMED CT concept]
- macrophage activating factor [SNOMED Notion]
Record concept(s)
- Macrophage-Activating factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- preGc1f1fMAF protein, human [MeSH Supplementary Concept]
- vitamin D-binding protein-macrophage activating factor [MeSH Supplementary Concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Macrophage activating factor (substance) [SNOMED CT concept]
- macrophage activating factor [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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