trichosanthin - CISMeF

Preferred Label : trichosanthin;

MeSH definition : Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.;

MeSH synonym : alpha-trichosanthin; alpha trichosanthin; compound q;

MeSH hyponym : GLQ-223; GLQ 223; GLQ223;

Related MeSH term : tian-hua-fen; T'ien-hua-fen;

MeSH CAS label : proteins, specific or class, trichosanthins;

Registry Number MeSH : 60318-52-7;

MeSH annotation : /drug eff /ultrastruct permitted;

Is substance : O;

Details

Origin ID

D015978;

UMLS CUI

C0040942;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 11-Deoxycorticosterone [LOINC component]
False automatic mappings
- Compound [NCIt concept]
- Compound (qualifier value) [SNOMED CT concept]
- Compound name [EDAM data]
- Desoxycorticosterone acetate (substance) [SNOMED CT concept]
- compound [SNOMED Notion]
Pharmacological action(s)
- abortifacient agents, nonsteroidal [MeSH Descriptor]
- anti-hiv agents [MeSH Descriptor]
- antineoplastic agents, phytogenic [MeSH Descriptor]
- antiviral agents [MeSH Descriptor]
- reproductive control agents [MeSH Descriptor]
Record concept(s)
- GLQ-223 [MeSH concept]
- tian-hua-fen [MeSH concept]
- trichosanthin [MeSH concept]
Related MeSH Supplementary Concept(s)
- beta-trichosanthin [MeSH Supplementary Concept]
- bromodextran-trichosanthin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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