MeSH definition : Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa
by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN).
Factor XIa then activates factor IX to factor IXa in the presence of calcium.;
Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa
by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN).
Factor XIa then activates factor IX to factor IXa in the presence of calcium.