complement C3a

Preferred Label : complement C3a;

MeSH definition : The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.;

MeSH synonym : complement 3a; complement component 3a; c3a, complement; component 3a, complement; c3a complement; complement, C3a;

MeSH CAS label : complement C3a;

Registry Number MeSH : 80295-42-7;

Wikipedia link : https://en.wikipedia.org/wiki/Complement c3a;

Is substance : O;

Details

Origin ID

D015926;

UMLS CUI

C0009510;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Complement C3a Measurement [NCIt concept]
Currated CISMeF NLP mapping
- Complement C3a [LOINC component]
- Complement component C3a (substance) [SNOMED CT concept]
- complement component c3a [SNOMED Notion]
Indexing information
- WWGKKYRASKLGCAR peptide [MeSH Supplementary Concept]
- complement C3a receptor [MeSH Supplementary Concept]
- leucyl-prolyl-leucyl-prolyl-arginine [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C3a [MeSH concept]
Related MeSH Supplementary Concept(s)
- complement C3a, (57-77) [MeSH Supplementary Concept]
- complement C3a, (70-77) [MeSH Supplementary Concept]
- complement C3a, (72-77) [MeSH Supplementary Concept]
- complement C3a, (Tyr-70-77) [MeSH Supplementary Concept]
- complement C3a, des-Arg-(77)- [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement C3a [LOINC component]
- Complement component C3a (substance) [SNOMED CT concept]
- complement component c3a [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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