4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine

Preferred Label : 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine;

MeSH definition : A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.;

MeSH hyponym : bw 755c; BW-755C; BW755C;

MeSH CAS label : 1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)-;

Registry Number MeSH : 66000-40-6;

Codes EINECS : 266-051-8;

Is substance : O;

Details

Origin ID

D015772;

UMLS CUI

C0949477;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-3-amine [Substance BNPC]
Pharmacological action(s)
- cyclooxygenase inhibitors [MeSH Descriptor]
- lipoxygenase inhibitors [MeSH Descriptor]
Record concept(s)
- 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine [MeSH concept]
- BW-755C [MeSH concept]
Related MeSH Supplementary Concept(s)
- N-(4-chloro-2-(trifluoromethyl)phenyl)-4,5-dihydro-1H-pyrazole-2-amine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-3-amine [Substance BNPC]

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