2-Amino-5-phosphonovalerate

Preferred Label : 2-Amino-5-phosphonovalerate;

MeSH definition : The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.;

MeSH synonym : 2-amino-5-phosphonopentanoate; 5-phosphononorvaline; 2 amino 5 phosphonopentanoic acid; 2 amino 5 phosphonopentanoate; 5 phosphononorvaline; 2-amino-5-phosphonovaleric acid; 2 amino 5 phosphonovaleric acid; 2-apv; 2-amino-5-phosphonopentanoic acid; 2 amino 5 phosphonovalerate;

Related MeSH term : dl-APV; d-APV;

MeSH CAS label : norvaline, 5-phosphono-;

Registry Number MeSH : 76726-92-6;

Wikipedia link : https://en.wikipedia.org/wiki/2-Amino-5-phosphonovalerate;

Is substance : O;

Details

Origin ID

D015763;

UMLS CUI

C0000254;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- excitatory amino acid antagonists [MeSH Descriptor]
- neurotransmitter agents [MeSH Descriptor]
Record concept(s)
- 2-Amino-5-phosphonovalerate [MeSH concept]
- d-APV [MeSH concept]
- dl-APV [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-amino-4-methyl-5-phosphono-3-pentenoic acid [MeSH Supplementary Concept]
- 2-amino-5-phosphono-3-pentenoic acid [MeSH Supplementary Concept]
- 2-amino-7-phosphonoheptanoic acid [MeSH Supplementary Concept]
- CGP 39551 [MeSH Supplementary Concept]
- CGP 39653 [MeSH Supplementary Concept]
- CGP 43487 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients