" /> giant cells - CISMeF





Preferred Label : giant cells;

MeSH definition : Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.;

MeSH synonym : cell, giant; cells, multinucleated giant; giant cells, multinucleated; multinucleated giant cells; syncytia; cells, giant; giant cell; syncytium; polykaryocytes; polykaryocyte; cell, multinucleated giant; giant cell, multinucleated; multinucleated giant cell;

MeSH annotation : any very large cell; A 11 qualif;

Wikipedia link : https://en.wikipedia.org/wiki/Syncytium;

Details


Keyword's position in hierarchy(ies) : arborescence

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Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.

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06/05/2025


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