Preferred Label : dna restriction-modification enzymes;
MeSH definition : Systems consisting of two enzymes, a modification methylase and a restriction endonuclease.
They are closely related in their specificity and protect the DNA of a given bacterial
species. The methylase adds methyl groups to adenine or cytosine residues in the same
target sequence that constitutes the restriction enzyme binding site. The methylation
renders the target site resistant to restriction, thereby protecting DNA against cleavage.;
MeSH synonym : modification systems, restriction; restriction-modification enzymes, dna; systems, restriction-modification; enzymes, dna restriction-modification; restriction-modification systems; restriction modification systems; systems, restriction modification; DNA restriction modification enzymes; DNA Restriction-Modification Enzyme; Enzyme, DNA Restriction-Modification; Restriction-Modification Enzyme, DNA; Restriction-Modification System; System, Restriction-Modification; Restriction Modification System; Modification System, Restriction; System, Restriction Modification; DNA Restriction Modification Enzyme;
MeSH annotation : DF: RESTRICT MOD ENZYMES;
Wikipedia link : https://en.wikipedia.org/wiki/Dna restriction-modification enzymes;
Is substance : O;
Origin ID : D015280;
UMLS CUI : C0012910;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
Systems consisting of two enzymes, a modification methylase and a restriction endonuclease.
They are closely related in their specificity and protect the DNA of a given bacterial
species. The methylase adds methyl groups to adenine or cytosine residues in the same
target sequence that constitutes the restriction enzyme binding site. The methylation
renders the target site resistant to restriction, thereby protecting DNA against cleavage.
