Preferred Label : arylsulfotransferase;
MeSH definition : A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate
as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number
of aromatic compounds can act as acceptors; however, organic hydroxylamines are not
substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation
of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.;
MeSH synonym : sulfokinase; sulfotransferase, aryl; aryl sulfotransferase; phenolsulfokinase; phenol sulfotransferase; sulfotransferase, phenol; phenol sulfokinase;
MeSH hyponym : catecholamine sulfotransferase B; dopamine sulfotransferase; catecholamine sulfotransferase A; flavonoid sulfotransferase; phenolsulfotransferase P; phenol sulfotransferase M; acetaminophen sulphotransferase; Sulfotransferase, Flavonoid; Sulfotransferase M, Phenol; Sulfotransferase B, Catecholamine; Sulphotransferase, Acetaminophen; Sulfotransferase A, Catecholamine; Sulfotransferase, Dopamine; Phenol Sulfotransferase P; Sulfotransferase P, Phenol;
MeSH CAS label : 3'-Phosphoadenylylsulfate:phenol sulfotransferase;
MeSH Related Number : 9026-09-9 (CAS RN);
Registry Number MeSH : EC 2.8.2.1;
Is substance : O;
UNII : EC 2.8.2.1;
Origin ID : D015239;
UMLS CUI : C0003942;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate
as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number
of aromatic compounds can act as acceptors; however, organic hydroxylamines are not
substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation
of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
