7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

Preferred Label : 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide;

MeSH definition : 7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity.;

MeSH synonym : benzo(a)pyrene 7,8-dihydrodiol 9,10-epoxide; benzo(a)pyrene-7,8-diol 9,10-epoxide; bpde; 7,8-bap-9,10-diol epoxide; 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene; anti-bapde; anti bapde;

MeSH CAS label : Benzo(10,11)chryseno(3,4-b)oxirene-7,8-diol, 7,8,8a,9a-tetrahydro-;

Registry Number MeSH : 55097-80-8;

MeSH annotation : a carcinogen & mutagen; D25-26 qualif; DF: 7 8 DDBP;

Is substance : O;

Details

Origin ID

D015123;

UMLS CUI

C0000641;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
Currated CISMeF NLP mapping
- Benzo(a)pyrene-7,8-diol 9,10-Epoxide [NCIt concept]
Pharmacological action(s)
- carcinogens [MeSH Descriptor]
- mutagens [MeSH Descriptor]
Record concept(s)
- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide [MeSH Supplementary Concept]
- 10-N(2)-deoxyguanosine-3-nitrobenzo(a)pyrene-7,8,9-triol [MeSH Supplementary Concept]
- 3-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide [MeSH Supplementary Concept]
- 7,8-dihydroxy-9,10-epoxide-7,8,9,10-tetrahydrobenzo(a)pyrene-10-deoxyguanosine [MeSH Supplementary Concept]
- 7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene-DNA adduct [MeSH Supplementary Concept]
- N(6)-(10-(7,8,9-trihydroxy-7,8,9,10-tetrahydrobenzo(a)pyrenyl))-2'-deoxyadenosine [MeSH Supplementary Concept]
- benz(a)pyrene-7,8-dihydrodiol-9,10-epoxide poly((dT-dC).(dG-dA)) adduct [MeSH Supplementary Concept]
- benzo(a)pyrene 7,8-dihydrodiol-9,10-epoxide poly((dA-dC).(dG-dT)) adduct [MeSH Supplementary Concept]
- benzo(a)pyrene 7,8-diol-9,10-epoxide-N2-deoxyguanosine [MeSH Supplementary Concept]
- benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA [MeSH Supplementary Concept]
- glutathione-BPDE conjugate [MeSH Supplementary Concept]
- poly(dG-dC)-benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Benzo(a)pyrene-7,8-diol 9,10-Epoxide [NCIt concept]

Keyword's position in hierarchy(ies) :

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