3',5'-Cyclic-AMP phosphodiesterases

Preferred Label : 3',5'-Cyclic-AMP phosphodiesterases;

MeSH definition : Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional spcificity for 3',5'-cyclic IMP and CYCLIC GMP.;

MeSH synonym : amp 5-nucleotidohydrolase, 3,5-cyclic; phosphodiesterase, camp; phosphodiesterase, 3',5'-cyclic amp; phosphodiesterase, 3,5-cyclic amp; phosphodiesterase, 3',5'-cyclic nucleotide; phosphodiesterase, 3',5'-cyclic-amp; phosphodiesterase, 3',5'-cyclic-nucleotide; phosphodiesterases, 3',5'-cyclic-amp; 3,5 cyclic amp phosphodiesterase; 3',5' cyclic nucleotide phosphodiesterase; 3',5' nucleotide phosphodiesterase; 3',5'-cyclic amp phosphodiesterase; 3,5-cyclic amp 5-nucleotidohydrolase; 5'-nucleotidohydrolase, 3',5'-cyclic amp; amp 5'-nucleotidohydrolase, 3',5'-cyclic; amp phosphodiesterase, 3',5'-cyclic; 3',5'-cyclic nucleotide phosphodiesterase; nucleotide phosphodiesterase, 3',5'-cyclic; 3',5'-cyclic-amp phosphodiesterase; 3',5'-nucleotide phosphodiesterase; phosphodiesterase, 3',5'-nucleotide; 3,5 cyclic amp 5 nucleotidohydrolase; 5-nucleotidohydrolase, 3,5-cyclic amp; 3,5-cyclic amp phosphodiesterase; amp phosphodiesterase, 3,5-cyclic; camp phosphodiesterase; 3',5' cyclic amp phosphodiesterase; 3',5'-cyclic-nucleotide phosphodiesterase; 3',5'-cyclic amp 5'-nucleotidohydrolase; 3',5' cyclic amp 5' nucleotidohydrolase; 3',5' cyclic AMP phosphodiesterases;

MeSH CAS label : 3',5'-Cyclic-nucleotide 5'-nucleotidohydrolase;

Registry Number MeSH : EC 3.1.4.17;

MeSH annotation : general; prefer specifics; DF: 3 5 CYCL NPD; general or unspecified; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide phosphodiesterase;

Is substance : O;

UNII : EC 3.1.4.17;

Details

Origin ID

D015105;

UMLS CUI

C0000359;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 2',3'-cyclic-nucleotide 2'-phosphodiesterase [SNOMED Notion]
- 2',3'-cyclic-nucleotide 2'-phosphodiesterase (substance) [SNOMED CT concept]
- 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO term]
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase [SNOMED Notion]
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase (substance) [SNOMED CT concept]
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO term]
- 3',5'-cyclic-nucleotide phosphodiesterase [SNOMED Notion]
- 3',5'-cyclic-nucleotide phosphodiesterase (substance) [SNOMED CT concept]
- cAMP-Specific 3',5'-Cyclic Phosphodiesterase 4B [NCIt concept]
Indexing information
- 2,4-diamino-5-cyano-6-bromopyridine [MeSH Supplementary Concept]
- 2,4-diamino-5-cyano-6-iodopyridine [MeSH Supplementary Concept]
- 2-(2-fluorobenzamido)benzoate ethyl ester [MeSH Supplementary Concept]
- 2-adamantan-2-yl-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one [MeSH Supplementary Concept]
- 2-trifluoromethyl-9-(2-fluorophenylmethyl)-N-methyladenine [MeSH Supplementary Concept]
- 4-(3,4-dibutoxybenzyl)-2-imidazolidinone [MeSH Supplementary Concept]
- 4-(4-(3,4-diethoxyphenyl)-1oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl)benzoic acid [MeSH Supplementary Concept]
- 7-chloro-5-propyl-1,2,4-triazolo(4,3-a)quinoxaline-1,4(2H,5H)-dione [MeSH Supplementary Concept]
- 8-aminohexylamino cAMP [MeSH Supplementary Concept]
- 9-cyclohexyl-2-n-propoxy-9H-adenine [MeSH Supplementary Concept]
- BAY 19-8004 [MeSH Supplementary Concept]
- BMY 21190 [MeSH Supplementary Concept]
- CK 2289 [MeSH Supplementary Concept]
- DTA 35 [MeSH Supplementary Concept]
- KS 504a [MeSH Supplementary Concept]
- KS 504d [MeSH Supplementary Concept]
- KS 504e [MeSH Supplementary Concept]
- RX-RA 69 [MeSH Supplementary Concept]
- U 84569 [MeSH Supplementary Concept]
- adenosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate [MeSH Supplementary Concept]
- filaminast [MeSH Supplementary Concept]
- griseolic acid [MeSH Supplementary Concept]
- griseolic acid B [MeSH Supplementary Concept]
- griseolic acid C [MeSH Supplementary Concept]
- inchinko-to [MeSH Supplementary Concept]
- longestin [MeSH Supplementary Concept]
- penta-O-ethylquercetin [MeSH Supplementary Concept]
- phthalazinol [MeSH Supplementary Concept]
- reticulol [MeSH Supplementary Concept]
- terferol [MeSH Supplementary Concept]
- tyrphostin 51 [MeSH Supplementary Concept]
- zaprinast [MeSH Supplementary Concept]
Record concept(s)
- 3',5'-Cyclic-AMP phosphodiesterases [MeSH concept]
Related MeSH Supplementary Concept(s)
- PDE8A protein, human [MeSH Supplementary Concept]
- PDE8A protein, rat [MeSH Supplementary Concept]
- PDE8B protein, human [MeSH Supplementary Concept]
- PDE9A protein, human [MeSH Supplementary Concept]
- PDEB1 protein, trypanosoma brucei [MeSH Supplementary Concept]
- Pde4a protein, rat [MeSH Supplementary Concept]
- Pde8a protein, mouse [MeSH Supplementary Concept]
- Pde9a protein, mouse [MeSH Supplementary Concept]
- Pde9a protein, rat [MeSH Supplementary Concept]
- regA protein, dictyostelium [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 3',5'-cyclic-nucleotide phosphodiesterase [SNOMED Notion]
- 3',5'-cyclic-nucleotide phosphodiesterase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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