2',5'-oligoadenylate synthetase

Preferred Label : 2',5'-oligoadenylate synthetase;

MeSH definition : An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions. EC 2.7.7.-.; An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.;

MeSH synonym : atp-(2'-5')oligo(a)adenylyltransferase; polymerase, 2',5'-oligoadenylate; synthetase, 2,5 oligoadenylate; 2,5 oligoadenylate polymerase; 2,5 oligoadenylate synthetase; 2',5'-oligoadenylate polymerase; synthetase, 2',5'-oligoadenylate; oligoadenylate polymerase, 2,5; polymerase, 2,5 oligoadenylate; 2',5' oligoadenylate polymerase; (2'-5')an polymerase; 2',5'-oligo(a) synthetase; 2',5'-oligo(a) polymerase; oligoadenylate synthetase, 2,5; 2-5a synthetase; 2',5' oligoadenylate synthetase;

CISMeF synonym : 2 5a synthetase;

Registry Number MeSH : EC 2.7.7.-; EC 2.7.7.84;

Is substance : O;

UNII : EC 2.7.7.84;

Details

Origin ID

D015088;

UMLS CUI

C0000189;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Nucleotidyltransferase [NCIt concept]
Record concept(s)
- 2',5'-Oligoadenylate synthetase [MeSH concept]
Related MeSH Supplementary Concept(s)
- OAS1 protein, human [MeSH Supplementary Concept]
- OAS2 protein, human [MeSH Supplementary Concept]
- OAS3 protein, human [MeSH Supplementary Concept]
- OASL protein, human [MeSH Supplementary Concept]
- Oas1b protein, mouse [MeSH Supplementary Concept]
- Oas1c protein, mouse [MeSH Supplementary Concept]
- Oas1d protein, mouse [MeSH Supplementary Concept]
- Oas1g protein, mouse [MeSH Supplementary Concept]
- Oasl1 protein, mouse [MeSH Supplementary Concept]
- Oasl2 protein, mouse [MeSH Supplementary Concept]
- p30 oligoadenylate synthetase [MeSH Supplementary Concept]
- p56 oligoadenylate synthetase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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