uncoupling agents

Preferred Label : uncoupling agents;

MeSH definition : Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.;

MeSH synonym : agents, uncoupling;

MeSH annotation : enzyme inhib;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D014475;

UMLS CUI

C0041658;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- DIO 9 [MeSH Supplementary Concept]
- carbonyl cyanide phenylhydrazone [MeSH Supplementary Concept]
Record concept(s)
- uncoupling agents [MeSH concept]
See also
- ionophores [MeSH Descriptor]
- oxidative phosphorylation [MeSH Descriptor]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 2,4-Dinitrophenol [MeSH Descriptor]
- 4,6-dinitro-o-cresol [MeSH Supplementary Concept]
- SF 6847 [MeSH Supplementary Concept]
- alamethicin [MeSH Descriptor]
- aurovertins [MeSH Descriptor]
- bathophenanthroline [MeSH Supplementary Concept]
- bis(1,10-phenanthroline)copper(2+) ion [MeSH Supplementary Concept]
- chlorphenamidine [MeSH Descriptor]
- dicumarol [MeSH Descriptor]
- dinitrophenols [MeSH Descriptor]
- ellipticine [MeSH Supplementary Concept]
- glyphosate [MeSH Supplementary Concept]
- oligomycins [MeSH Descriptor]
- pentachlorophenol [MeSH Descriptor]
- picric acid [MeSH Supplementary Concept]
- rotenone [MeSH Descriptor]
- rutamycin [MeSH Descriptor]
- tetraphenylborate [MeSH Descriptor]
- venturicidins [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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