toyocamycin - CISMeF

Preferred Label : toyocamycin;

MeSH definition : 4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.;

MeSH synonym : toyokamycin; deazacyanoadenosine;

MeSH CAS label : 7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-beta-D-ribofuranosyl-;

MeSH Related Number : 606-58-6 (Toyocamycin);

Registry Number MeSH : 606-58-6;

MeSH annotation : an antineoplastic antibiotic & antimetabolite;

Is substance : O;

UNII : L7995C4D7F;

InChIKey : XOKJUSAYZUAMGJ-WOUKDFQISA-N;

Details

Origin ID

D014127;

UMLS CUI

C0040562;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Toyocamycin [SMS substance]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- antimetabolites, antineoplastic [MeSH Descriptor]
Record concept(s)
- toyocamycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2'-deoxytoyocamycin-5'-triphosphate [MeSH Supplementary Concept]
- 5'-deoxytoyocamycin [MeSH Supplementary Concept]
- MCS-C2 [MeSH Supplementary Concept]
- thiotoyocamycin [MeSH Supplementary Concept]
- toyocamycin 3',5'-cyclic phosphate [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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