thromboxane A2

Preferred Label : thromboxane A2;

MeSH definition : An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).;

MeSH synonym : a2, thromboxane;

MeSH Hyperonym : rabbit aorta contracting substance;

MeSH CAS label : Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-;

Registry Number MeSH : 57576-52-0;

MeSH annotation : /biosyn /physiol permitted;

Is substance : O;

Details

Origin ID

D013928;

UMLS CUI

C0040057;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Thromboxane A2 [NCIt concept]
- thromboxane [Artificial nutrition thesaurus concept]
- thromboxane, nos [SNOMED Notion]
Currated CISMeF NLP mapping
- Thromboxane A>2< (substance) [SNOMED CT concept]
- Thromboxane alpha 2 [LOINC component]
- thromboxane a2 [SNOMED Notion]
Indexing information
- 7-(2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl)heptenoic acid [MeSH Supplementary Concept]
- 9-fluoro-15-hydroxy-16-phenoxy-17,18,19,20-tetranor-5,13-prostadienoic acid [MeSH Supplementary Concept]
- KDI 792 [MeSH Supplementary Concept]
- RCS-RF [MeSH Supplementary Concept]
Record concept(s)
- rabbit aorta contracting substance [MeSH concept]
- thromboxane A2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- 10,10-difluorothromboxane A2 [MeSH Supplementary Concept]
- 15-hydroperoxythromboxane A2 [MeSH Supplementary Concept]
- 9,10-dimethylmethano-11,12-methano-16-(4-methoxyphenyl)-13,14-dihydro-13-aza-15-tetranorthromboxane A2 [MeSH Supplementary Concept]
- 9,11-dimethylmethano-11,12-methano-16-(3-iodo-4-azidophenyl)-13,14-dihydro-13-aza-15-tetranorthromboxane A2 [MeSH Supplementary Concept]
- EP 171 [MeSH Supplementary Concept]
- I-PTA-OH [MeSH Supplementary Concept]
- ONO 11006 [MeSH Supplementary Concept]
- ONO 11105 [MeSH Supplementary Concept]
- ONO 11119 [MeSH Supplementary Concept]
- ONO 11120 [MeSH Supplementary Concept]
- ONO 3708 [MeSH Supplementary Concept]
- SQ 28668 [MeSH Supplementary Concept]
- SQ 30741 [MeSH Supplementary Concept]
- STA 2 [MeSH Supplementary Concept]
- pinane-thromboxane A2 [MeSH Supplementary Concept]
- thromboxane A2, carbocyclic [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Thromboxane A2 [NCIt concept]
- Thromboxane A>2< (substance) [SNOMED CT concept]
- Thromboxane alpha 2 [LOINC component]
- thromboxane a2 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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