tenuazonic acid

Preferred Label : tenuazonic acid;

MeSH definition : 3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.;

MeSH synonym : acid, tenuazonic;

MeSH CAS label : 2H-Pyrrol-2-one, 3-acetyl-1,5-dihydro-4-hydroxy-5-(1-methylpropyl)-, (S-(R*,R*))-;

Registry Number MeSH : 610-88-8;

MeSH annotation : an antineoplastic antibiotic;

Wikipedia link : https://en.wikipedia.org/wiki/Tenuazonic acid;

Is substance : O;

Details

Origin ID

D013720;

UMLS CUI

C0039531;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Tenuazonic acid [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Tenuazonic Acid [NCIt concept]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- antiviral agents [MeSH Descriptor]
Record concept(s)
- tenuazonic acid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-acetyl-5-iso-butyltetramic acid [MeSH Supplementary Concept]
- 3-acetyl-5-isopropyltetramic acid [MeSH Supplementary Concept]
- F-14329 [MeSH Supplementary Concept]
- reutericyclin [MeSH Supplementary Concept]
- tolypoalbin [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Tenuazonic Acid [NCIt concept]

Keyword's position in hierarchy(ies) :

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