Preferred Label : spleen focus-forming viruses;
MeSH definition : Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming.
The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA,
ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA.
Spleen focus-forming viruses are generated by recombination with endogenous retroviral
sequences.;
MeSH synonym : focus-forming virus, spleen; spleen focus-forming virus; focus-forming viruses, spleen; sffv; spleen focus forming viruses;
MeSH hyponym : rauscher spleen Focus-Forming virus; friend spleen focus-forming virus; Friend spleen focus forming virus;
MeSH Related Number : txid11820; txid11821;
MeSH annotation : infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) TUMOR VIRUS INFECTIONS
(IM) LEUKEMIA, EXPERIMENTAL (IM) or LEUKEMIA, ERYTHROBLASTIC, ACUTE (IM) (for spontaneous
erythroleukemia);
UNII : txid11819;
Origin ID : D013155;
UMLS CUI : C0037994;
Allowable qualifiers
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
Semantic type(s)
- Virus [UMLS semantic type]
UMLS correspondences (same concept)
Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming.
The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA,
ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA.
Spleen focus-forming viruses are generated by recombination with endogenous retroviral
sequences.