MeSH definition : Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise
anywhere on the body, but are most frequently found over the bony prominences. The
nodules are characterized histologically by dense areas of fibrinoid necrosis with
basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts
and histiocytes.;
Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise
anywhere on the body, but are most frequently found over the bony prominences. The
nodules are characterized histologically by dense areas of fibrinoid necrosis with
basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts
and histiocytes.