Preferred Label : retinaldehyde;
MeSH definition : A carotenoid constituent of visual pigments. It is the oxidized form of retinol which
functions as the active component of the visual cycle. It is bound to the protein
opsin forming the complex rhodopsin. When stimulated by visible light, the retinal
component of the rhodopsin complex undergoes isomerization at the 11-position of the
double bond to the cis-form; this is reversed in dark reactions to return to the native
trans-configuration.; A diterpene derived from the carotenoid VITAMIN A which functions as the active component
of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded
to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms
this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation
straightens-out the bend of the retinal molecule and causes a change in the shape
of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed
reactions convert the 11-trans-retinal back to the cis-isomer.;
MeSH synonym : aldehyde, vitamin a; axerophthal; retinene; vitamin a aldehyde; Retinal; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal; Retinyl Aldehydde; Aldehydde, Retinyl;
MeSH hyponym : 11-cis-Retinal; 11 cis Retinal; 11 trans Retinal; all-trans-Retinal; all trans Retinal;
MeSH CAS label : retinal;
MeSH Related Number : 116-31-4 (Retinaldehyde);
Registry Number MeSH : 116-31-4;
MeSH annotation : /biosyn /physiol permitted;
Wikipedia link : https://en.wikipedia.org/wiki/Retinal;
Codes EINECS : 204-135-8;
Is substance : O;
UNII : RR725D715M;
InChIKey : NCYCYZXNIZJOKI-OVSJKPMPSA-N;
Origin ID : D012172;
UMLS CUI : C0035331;
Allowable qualifiers
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- False automatic mappings
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A carotenoid constituent of visual pigments. It is the oxidized form of retinol which
functions as the active component of the visual cycle. It is bound to the protein
opsin forming the complex rhodopsin. When stimulated by visible light, the retinal
component of the rhodopsin complex undergoes isomerization at the 11-position of the
double bond to the cis-form; this is reversed in dark reactions to return to the native
trans-configuration.
A diterpene derived from the carotenoid VITAMIN A which functions as the active component
of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded
to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms
this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation
straightens-out the bend of the retinal molecule and causes a change in the shape
of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed
reactions convert the 11-trans-retinal back to the cis-isomer.
