quinone reductases

Preferred Label : quinone reductases;

MeSH definition : NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.;

MeSH synonym : reductases, quinone;

MeSH hyponym : menaquinone reductases; Reductases, Menaquinone;

Registry Number MeSH : EC 1.6.99.-;

Is substance : O;

Details

Origin ID

D011808;

UMLS CUI

C0034434;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone) (substance) [SNOMED CT concept]
- nad(p)h dehydrogenase (quinone) [SNOMED Notion]
Indexing information
- 6-methoxy-9-methyl-(1,3)dioxolo(4,5-h)quinolin-8(9H)-one [MeSH Supplementary Concept]
Record concept(s)
- menaquinone reductases [MeSH concept]
- quinone reductases [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,4-benzoquinone reductase [MeSH Supplementary Concept]
- FQR1 protein, arabidopsis [MeSH Supplementary Concept]
- NADH dehydrogenase (quinone) [MeSH Supplementary Concept]
- NADH duroquinone reductase [MeSH Supplementary Concept]
- NADPH - phenanthrenequinone oxidoreductase [MeSH Supplementary Concept]
- NRH - quinone oxidoreductase2 [MeSH Supplementary Concept]
- NuoF protein, E coli [MeSH Supplementary Concept]
- YCR102C protein, S cerevisiae [MeSH Supplementary Concept]
- YhdH protein, E coli [MeSH Supplementary Concept]
- Zta1 protein, S cerevisiae [MeSH Supplementary Concept]
- benzo(a)pyrene-3,6-quinone reductase [MeSH Supplementary Concept]
- coenzyme F420H2 - 2,3-dimethyl-1,4-naphthoquinone oxidoreductase [MeSH Supplementary Concept]
- dichlorophenolindophenol reductase [MeSH Supplementary Concept]
- dinitropyrene nitroreductase [MeSH Supplementary Concept]
- hydroxyhydroquinone reductase [MeSH Supplementary Concept]
- isochromanequinone reductase [MeSH Supplementary Concept]
- photooxidase, rhodospirillum rubrum [MeSH Supplementary Concept]
- sodium-translocating NADH-quinone reductase [MeSH Supplementary Concept]
- sulfide quinone reductase [MeSH Supplementary Concept]
- tetrachlorobenzoquinone reductase, Sphingobium chlorophenolicum [MeSH Supplementary Concept]
- ubiquinol-1 oxidase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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