pyruvate decarboxylase

Preferred Label : pyruvate decarboxylase;

MeSH definition : Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.;

MeSH synonym : 2 oxo acid carboxy lyase; carboxy-lyase, 2-oxo acid; carboxylase, alpha-ketoacid; Alpha-ketoacid carboxylase; alpha ketoacid carboxylase; acid carboxy-lyase, 2-oxo; alpha carboxylase; alpha-carboxylase; decarboxylase, pyruvate; decarboxylase, pyruvic; pyruvic decarboxylase; 2-oxo acid carboxy-lyase;

CISMeF synonym : 2-oxo-acid carboxy-lyase;

MeSH Related Number : 9001-04-1 (CAS RN);

Registry Number MeSH : EC 4.1.1.1;

Wikipedia link : https://en.wikipedia.org/wiki/Pyruvate decarboxylase;

Is substance : O;

UNII : EC 4.1.1.1;

Details

Origin ID

D011767;

UMLS CUI

C0034342;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Pyruvate decarboxylase (substance) [SNOMED CT concept]
- Vitamin K Epoxide Reductase Complex Subunit 1 [NCIt concept]
- pyruvate decarboxylase [SNOMED Notion]
Indexing information
- 4-(4-chlorophenyl)-2-oxo-3-butenoic acid [MeSH Supplementary Concept]
- Thi3 protein, S cerevisiae [MeSH Supplementary Concept]
Record concept(s)
- pyruvate decarboxylase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ARO10 protein, S cerevisiae [MeSH Supplementary Concept]
- CFP protein, neurospora crassa [MeSH Supplementary Concept]
- IAR4 protein, arabidopsis [MeSH Supplementary Concept]
- PDC1 protein, S cerevisiae [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Pyruvate decarboxylase (substance) [SNOMED CT concept]
- pyruvate decarboxylase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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