pyroglutamate hydrolase

Preferred Label : pyroglutamate hydrolase;

MeSH definition : Hydrolyzes pyroglutamic acid in the presence of ATP to glutamate plus ADP and inorganic phosphate. Deficiency leads to pyroglutamic acidurea.;

MeSH synonym : hydrolase, pyroglutamate; 5 oxoprolinase; 5-oxoprolinase; oxoprolinase;

Registry Number MeSH : EC 3.5.2.-;

Is substance : O;

Details

Origin ID

D011752;

UMLS CUI

C0034308;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5-oxoprolinase, ATP-hydrolysing [ORDO Gene]
Indexing information
- 2-imidazolidone-4-carboxylic acid [MeSH Supplementary Concept]
Record concept(s)
- pyroglutamate hydrolase [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5-oxoprolinase deficiency [MeSH Supplementary Concept]
See also inter- (CISMeF)
- 5-oxoprolinase (adenosine triphosphate-hydrolysing) (substance) [SNOMED CT concept]
- 5-oxoprolinase (atp-hydrolysing) [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 5-oxoprolinase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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