platelet activating factor

Preferred Label : platelet activating factor;

MeSH definition : A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.;

MeSH synonym : 1-alkyl-2-acetyl-sn-glycerophosphocholine; platelet-activating substance; paf acether; phosphorylcholine, acetyl glyceryl ether; platelet aggregation enhancing factor; factor, platelet activating; platelet aggregating factor; aggregating factor, platelet; acetyl glyceryl ether phosphorylcholine; agepc; paf-acether; 1 alkyl 2 acetyl sn glycerophosphocholine; platelet activating substance; thrombocyte aggregating activity;

Wikipedia automatic translation : Platelet-activating factor;

Wikipedia link : https://en.wikipedia.org/wiki/Platelet-activating factor;

Is substance : O;

Details

Origin ID

D010972;

UMLS CUI

C0032172;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Factor [NCIt concept]
- Mathematical Factor [NCIt concept]
- Platelet Activating Factor Measurement [NCIt concept]
- Postman (occupation) [SNOMED CT concept]
- factor [IUPAC Term]
- positive regulation of platelet aggregation [GO term]
- postman [SNOMED Notion]
Currated CISMeF NLP mapping
- Platelet Activating Factor [NCIt concept]
- Platelet activating factor (substance) [SNOMED CT concept]
- platelet activating factor [SNOMED Notion]
Indexing information
- 1-((1-(3-(4-aminophenyl)-3-phenylpropenoyl)-4-piperidyl)methyl)-1H-2-methylimidazo(4,5-c)pyridine [MeSH Supplementary Concept]
- 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 2,5-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane [MeSH Supplementary Concept]
- 2-hydroxy-3-methoxybenzoic acid glucose ester [MeSH Supplementary Concept]
- 2-methyl-1-phenylimidazo(4,5-c)pyridine [MeSH Supplementary Concept]
- ONO 6240 [MeSH Supplementary Concept]
- PAFAH1B1 protein, human [MeSH Supplementary Concept]
- PAFAH1B2 protein, human [MeSH Supplementary Concept]
- PCA 4233 [MeSH Supplementary Concept]
- PMS 601 [MeSH Supplementary Concept]
- SAH 63-675 [MeSH Supplementary Concept]
- SR 27388 [MeSH Supplementary Concept]
- UR 12670 [MeSH Supplementary Concept]
- UR 12746 [MeSH Supplementary Concept]
- YM 264 [MeSH Supplementary Concept]
- YM 461 [MeSH Supplementary Concept]
- abbott 84768 [MeSH Supplementary Concept]
- cinerin A [MeSH Supplementary Concept]
- cinerin B [MeSH Supplementary Concept]
- cinerin C [MeSH Supplementary Concept]
- ginkgolide B [MeSH Supplementary Concept]
- lexipafant [MeSH Supplementary Concept]
- magnone A [MeSH Supplementary Concept]
- magnone B [MeSH Supplementary Concept]
- paeonilide [MeSH Supplementary Concept]
- phomactin A [MeSH Supplementary Concept]
- phomactin D [MeSH Supplementary Concept]
- phomactin E [MeSH Supplementary Concept]
- phomactin F [MeSH Supplementary Concept]
- phomactin G [MeSH Supplementary Concept]
- pinusolidic acid [MeSH Supplementary Concept]
- platelet activating factor receptor [MeSH Supplementary Concept]
- rupatadine [MeSH Supplementary Concept]
- sch 44643 [MeSH Supplementary Concept]
Record concept(s)
- platelet activating factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine [MeSH Supplementary Concept]
- 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine [MeSH Supplementary Concept]
- 1-O-(2-methyloctadecyl)-2-O-acetyl-rac-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-(4-azido-2-hydroxy-3-iodobenzamido)undecyl-2-O-acetyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-alkyl-2-O-ethyl-sn-glyceryl-3-phosphorylcholine [MeSH Supplementary Concept]
- 1-O-alkyl-2-propionyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-docosyl-2-O-acetylglycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadec-1'-enyl-2-acetyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-C,O-dimethylglycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-C-methyl-3-phosphatidylcholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-O-N,N-dimethylcarbamoyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-O-ethyl-rac-glycero-3-phosphoric acid 4-(N,N-dimethylamino)-pyridinium ethylester [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-acetyl-3-thiophosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphono(N,N,N-trimethyl)hexanolamine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-acrylyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-hydroxypropane-3-phosphonocholine [MeSH Supplementary Concept]
- 1-O-hexadecyl-2-lyso-glycero-3-phosphorylcholine [MeSH Supplementary Concept]
- 1-O-hexadecylglycerophosphocholine [MeSH Supplementary Concept]
- 1-O-octadecyl-2-O-(2-inositolylethyl)-glycero-3-phosphatidylcholine [MeSH Supplementary Concept]
- 1-acyl-2-acetyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-alkyl-2-acyl-sn-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 1-hexadecyl-2-acetyl-glycero-3-phosphocholine [MeSH Supplementary Concept]
- 2-acetyl-S-octadecyl-1-thioglycero-3-phosphocholine [MeSH Supplementary Concept]
- 2-isobutyl-platelet activating factor [MeSH Supplementary Concept]
- 2-isopropyl-platelet activating factor [MeSH Supplementary Concept]
- 2-methyl carbamate-platelet activating factor [MeSH Supplementary Concept]
- 2-n-propyl-platelet activating factor [MeSH Supplementary Concept]
- 3-((3-(acetyloxy)-4-(hexadecyloxy)butyl)sulfonyl)-N,N,N-trimethyl-1-propanaminium [MeSH Supplementary Concept]
- BN 52719 [MeSH Supplementary Concept]
- O-deacetyl platelet activating factor [MeSH Supplementary Concept]
- SDZ 64-688 [MeSH Supplementary Concept]
- U 66982 [MeSH Supplementary Concept]
- U 66985 [MeSH Supplementary Concept]
- dansyl-platelet activating factor [MeSH Supplementary Concept]
- phosphono-platelet activating factor [MeSH Supplementary Concept]
- platelet activating factor phosphatidate [MeSH Supplementary Concept]
- platelet activating factor-amidophosphonate [MeSH Supplementary Concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Platelet Activating Factor [NCIt concept]
- Platelet activating factor (substance) [SNOMED CT concept]
- platelet activating factor [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients