pepsin A - CISMeF

Preferred Label : pepsin A;

MeSH definition : Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.;

MeSH synonym : pepsin;

MeSH hyponym : pepsin 1; pepsin 3;

MeSH Related Number : 9001-75-6 (CAS RN);

Registry Number MeSH : EC 3.4.23.1;

MeSH annotation : /biosyn /physiol permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Pepsin a;

Is substance : O;

UNII : EC 3.4.23.1;

Details

Origin ID

D010434;

UMLS CUI

C0030909;

ATC code(s)
- pepsin [ATC Code]
- pepsin and acid preparations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Pepsin poisoning (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Pepsin [LOINC component]
- Pepsin [ICHI extension code]
- Pepsin A (substance) [SNOMED CT concept]
- pepsin a [SNOMED Notion]
Indexing information
- H 256 [MeSH Supplementary Concept]
- ecabet [MeSH Supplementary Concept]
- pepsin inhibitor PI-3 [MeSH Supplementary Concept]
- pepstanone A [MeSH Supplementary Concept]
- phenylalanyl-glycyl-histidyl-statyl-alanyl-phenylalanine methyl ester [MeSH Supplementary Concept]
- phenylalanyl-glycyl-valyl-statyl-alanyl-phenylalanine methyl ester [MeSH Supplementary Concept]
- streptomyces pepsin inhibitor [MeSH Supplementary Concept]
- valyl-leucyl-prolyl-phenylalanyl-phenylalanyl-valyl-leucine [MeSH Supplementary Concept]
Manual BTNT mappings - CISMeF
- Pepsin digestant [ICD-11 Extension code]
Pharmacological action(s)
- gastrointestinal agents [MeSH Descriptor]
Record concept(s)
- pepsin 1 [MeSH concept]
- pepsin 3 [MeSH concept]
- pepsin A [MeSH concept]
Related MeSH Supplementary Concept(s)
- diazoacetylglycine ethyl ester-pepsin [MeSH Supplementary Concept]
- diskilene [MeSH Supplementary Concept]
- gastricsin [MeSH Supplementary Concept]
- pepsin B [MeSH Supplementary Concept]
- spasmocanulase [MeSH Supplementary Concept]
See also
- gastric juice [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pepsin [ICD-11 Extension code]
- Pepsin [LOINC component]
- Pepsin A (substance) [SNOMED CT concept]
- Product containing pepsin A (medicinal product) [SNOMED CT concept]
- pepsin [ATC Code]
- pepsin a [SNOMED Notion]
Validated automatic mappings to NTBT
- Pepsin [ICD-11 Extension code]

Keyword's position in hierarchy(ies) :

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