Preferred Label : pancreatic polypeptide;
MeSH definition : A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found
at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN
and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress
gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A
lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.;
MeSH synonym : pancreatic polypeptide (pp); pancreatic polypeptide hormone;
MeSH Hyperonym : pancreatic prohormone;
Registry Number MeSH : 59763-91-6;
Wikipedia link : https://en.wikipedia.org/wiki/Pancreatic polypeptide;
Is substance : O;
Origin ID : D010191;
UMLS CUI : C0030298;
Allowable qualifiers
Currated CISMeF NLP mapping
Indexing information
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- PP 1420 [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found
at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN
and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress
gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A
lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.