pactamycin - CISMeF

Preferred Label : pactamycin;

MeSH definition : Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.;

MeSH CAS label : benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))-;

Registry Number MeSH : 23668-11-3;

Is substance : O;

Details

Origin ID

D010142;

UMLS CUI

C0030178;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- protein synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- pactamycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5''-fluoropactamycin [MeSH Supplementary Concept]
- 8''-hydroxypactamycin [MeSH Supplementary Concept]
- TM-025 [MeSH Supplementary Concept]
- TM-026 [MeSH Supplementary Concept]
- cranomycin [MeSH Supplementary Concept]
- jogyamycin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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