fenclonine - CISMeF

Preferred Label : fenclonine;

MeSH definition : A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.;

MeSH synonym : para chlorophenylalanine; fenclonin; p-chlorophenylalanine; para-chlorophenylalanine; dl-3-(4-chlorophenyl)alanine;

MeSH hyponym : fenclonine hydrobromide; fenclonine, (D)-Isomer; CP-10,188; fenclonine (L)-Isomer; fenclonine hydrochloride; Hydrobromide, Fenclonine; Hydrochloride, Fenclonine;

MeSH CAS label : DL-Phenylalanine, 4-chloro-;

MeSH Related Number : fenclonine (L)-Isomer; fenclonine hydrochloride; fenclonine, (D)-Isomer; fenclonine hydrobromide; 14091-08-8 ((D)-isomer); 14173-39-8 ((L)-isomer); 1991-78-2 (cpd w/o isomeric designation); 23633-07-0 (cpd w/o isomeric designation, HCl); 51274-82-9 (HCl); 55327-86-1 (HBr); 7424-00-2 (Fenclonine);

Registry Number MeSH : 7424-00-2;

Related CAS MeSH : 14173-39-8 (Fenclonine (L)-Isomer); 51274-82-9 (Fenclonine hydrochloride); 14091-08-8 (Fenclonine, (D)-Isomer); 55327-86-1 (Fenclonine hydrobromide);

Wikipedia link : https://en.wikipedia.org/wiki/Fenclonine;

Codes EINECS : 231-051-9;

Is substance : O;

UNII : R5J7E3L9SP;

InChIKey : NIGWMJHCCYYCSF-UHFFFAOYSA-N;

Details

Origin ID

D010134;

UMLS CUI

C0030135;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- fenclonine [Substance BNPC]
Currated CISMeF NLP mapping
- Fenclonine [NCIt concept]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
- serotonin antagonists [MeSH Descriptor]
Record concept(s)
- CP-10,188 [MeSH concept]
- fenclonine [MeSH concept]
- fenclonine (L)-Isomer [MeSH concept]
- fenclonine hydrobromide [MeSH concept]
- fenclonine hydrochloride [MeSH concept]
- fenclonine, (D)-Isomer [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-chlorophenylalanine ethyl ester [MeSH Supplementary Concept]
- 4-chlorophenylalanine methyl ester [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fenclonine [NCIt concept]
- fenclonine [Substance BNPC]

Keyword's position in hierarchy(ies) :

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